They Might Be Giants
(1971, George C Scott, Joanne Woodward)
Scott plays a man who is convinced he is Sherlock Holmes. His doctor, played by Woodward, is called Watson. Set and filmed in New York, hence the background of New York City Transit Authority GM 'New Look' Fishbowls. The only identifiable example is 8190, a 1966 TDH-5303 model:
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