(1993, Robin Williams, Sally Field)
Early in the movie there's an appearance by this 1987 International S-1700:
Williams as Mrs Doubtfire boards San Francisco Muni 8922, a 1988 New Flier D40: She is chatted up by the driver, but that unfortunate soul is put off when he spots Mrs Doubtfire's hairy knees (thanks Chris Hough):
One scene has Mrs Doubtfire hanging off the side of San Francisco cable car 23: